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When it comes to erectile dysfunction medication, three main prescription treatments are available and have been effectively used for decades.

Deciding which treatment is right for you can depend on several factors, including your overall health and if you are taking any other medication, such as antibiotics. These physical health factors will determine which medication is right for you.

Before you order vardenafil, tadalafil or sildenafil online, here are the facts you need to know.

What Is Similar About Them?

There are several treatments for erectile dysfunction, however the most common and most trusted come in the form of PDE5 inhibitors. These drugs work to stimulate blood flow to the penis and trap it there, helping to maintain an erection.

PDE5 inhibitors do not work unless you are aroused and are often, though not always, taken as needed before sex. They can be taken with food, although they don’t need to be, and if taken with a food that’s high in fat can take longer to take effect

 Despite being similar in several ways, they also have some fundamental differences.


Sildenafil, more commonly known as Viagra, was the very first erectile dysfunction medication on the market and was discovered mostly by accident. It was formulated initially as a treatment for angina but turned out to be more effective for ED.

It is available as an oral tablet, generally blue in colour, that comes in 25mg, 50mg and 100mg, although the 50mg pill is the most well known and commonly used.

There is also a lower dose version used to treat cardiovascular diseases known as Revatio, which works in a similar way to improve blood flow more generally around the body.

It is effective for up to four hours, although this can vary on the individual.


Tadalafil, the generic name for Cialis works on the same principle as sildenafil in that it is also a PDE5 inhibitor, however, its effect on the body is very different and the doses are far lower.

The key difference is that whilst you can take it as needed in doses that start at 10mg, you can also take tadalafil with a daily dose starting at 2.5mg.

Daily dosages can be easier for some men as you do not need to plan around waiting for the medication to be digested and activate.

You do still need to wait 30 minutes after taking the pill before having sex, similar to sildenafil, however, the drug stays in your system for up to 36 hours.

Cialis is also used to treat benign prostatic hyperplasia, known as enlarged prostate, which can make both sexual activity and urination difficult.


Vardenafil, known most commonly as either Vivanza or Levitra, is effective for both erectile dysfunction, under similar principles to the other two tables, but also can be used for treating premature ejaculation as well as erectile dysfunction.

It must be taken 60 minutes before sex and the doses are far smaller compared to sildenafil, with the 50mg dose equivalent being just 10mg, and available in doses as low as 5mg.