If you’ve been using sildenafil (Viagra) for erectile dysfunction (ED) but aren’t completely satisfied with the results, you may be wondering whether it’s possible to switch to tadalafil (the cheap generic version of Cialis).
For many men, changing from one ED medication to another is straightforward following an appropriate medical assessment.
Although sildenafil and tadalafil belong to the same class of medicines, they work slightly differently. Some men find one suits their lifestyle better than the other, while others experience fewer side effects or prefer the duration of action.
Here’s what you should know before making the switch.
Why might someone switch erectile dysfunction medication?
There isn’t a single erectile dysfunction treatment that works best for everyone. Your response can depend on factors such as your overall health, lifestyle, other medications and personal preferences.
Some common reasons men consider switching from sildenafil to tadalafil include:
- Wanting a longer-lasting effect
- Finding it difficult to plan intimacy around taking medication
- Experiencing side effects with sildenafil
- Feeling sildenafil isn’t producing the desired results
- Looking for a treatment that offers greater spontaneity
Changing medication doesn’t necessarily mean the first treatment has failed. It often reflects finding the option that best fits your individual needs.
What’s the difference between sildenafil and tadalafil?
Both medications improve blood flow to the penis by relaxing blood vessels, making it easier to achieve and maintain an erection when sexually stimulated. However, there are some important differences.
Sildenafil
Sildenafil usually starts working within 30 to 60 minutes and remains effective for around four to six hours. It’s often recommended to take it on an empty stomach, as a heavy meal can delay absorption and reduce how quickly it works.
Many men find sildenafil highly effective, particularly when intimacy can be planned in advance.
Tadalafil
Tadalafil also begins working within approximately 30 to 60 minutes, but its effects can last for up to 36 hours. This longer window has earned it the nickname ‘the weekend pill.’
Because the medication remains active for much longer, many men appreciate having greater flexibility without feeling they need to carefully time intimacy. Tadalafil is also less affected by food than sildenafil, making it a convenient option for some users.
Does tadalafil work better than sildenafil?
Not necessarily. Clinical studies show both medications are highly effective at treating erectile dysfunction. Rather than one being universally ‘better,’ the right choice depends on your circumstances.
Some men prefer sildenafil because:
- It has a shorter duration
- They only need occasional treatment
- They have used it successfully for years
Others prefer tadalafil because:
- The longer duration feels more natural
- It allows for greater spontaneity
- They don’t have to plan as precisely
Your healthcare provider can help determine which option is most appropriate.
Can you change directly from sildenafil to tadalafil?
In many cases, yes. If your clinician determines tadalafil is suitable, you can usually stop using sildenafil and begin tadalafil as directed.
However, you should never take both medications together or overlap doses unless specifically instructed by a healthcare professional. Taking both PDE5 inhibitors at the same time increases the risk of side effects without improving effectiveness.
Your consultation will consider:
- Your medical history
- Current medications
- Heart health
- Blood pressure
- Previous experience with ED medication
- Any side effects you’ve experienced
What if sildenafil isn’t working?
If sildenafil hasn’t produced the results you expected, it doesn’t automatically mean you need a different medication.
Common reasons it may seem ineffective include:
- Taking it after a large meal
- Not allowing enough time for it to work
- Drinking excessive alcohol beforehand
- Insufficient sexual stimulation
- Using an incorrect dose
- Expecting immediate results after the first tablet
Many men need to try sildenafil on several separate occasions before deciding whether it works well for them. If problems continue, your clinician may recommend adjusting the dose or considering tadalafil instead.
Is tadalafil available as a daily tablet?
Yes, one feature that makes tadalafil different is that it can be prescribed as a low-dose daily tablet for suitable patients.
Rather than taking medication before anticipated sexual activity, a daily dose maintains a consistent level of the medicine in your body, allowing for greater spontaneity.
This option isn’t appropriate for everyone, but it can be particularly beneficial for men who have sex more frequently or prefer not to think about timing their medication.
Should you switch erectile dysfunction medication?
If you’re generally happy with sildenafil, there may be no reason to change.
However, if you would like:
- Longer-lasting effects
- More flexibility
- Fewer side effects
- A treatment that better fits your lifestyle
then tadalafil may be worth considering.
The decision should always be made following a consultation with a qualified prescriber, who can assess your medical history and recommend the safest and most effective option.